Anthony Edwards (left) with Tom Cruise (right) in 'Top Gun'
Anthony Edwards (1962 - )
Top Gun (1986) [Lt. JG Nick 'Goose' Bradshaw]: Hits his head on the canopy as he and Tom Cruise eject from the plane. (Thanks to Tal, Marigen, and Chris)

Miracle Mile (1988) [Harry Washello]: Either drowned (along with Mare Winningham) after their helicopter crashes into the LaBrea tar pits, or killed in an explosion when the nuclear missiles hit the city; the movie ends with them sinking into the tar, followed by the blast, so it's ambiguous which of the two events killed them. (Thanks to Kyle)

ER: The Letter/On the Beach (2002) [Dr. Mark Greene]: Dies of a brain tumor, with Alex Kingston by his side. (His death was reported in The Letter, when the rest of the hospital staff was informed; it was shown in the following episode On the Beach.) (Thanks to Tal, Marigen, Sara, Loes, and Chris)
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